As skin ages, collagen production slows. Environmental and other stressors damage the collagen bonds beyond the body's ability to repair them. This damage to the net causes the glycan network to thin and gradually lose its ability to retain water until it collapses on itself. The gel sags, pulling the epidermis with it. The result: dry, thin, wrinkled, sagging skin. Nutrients can no longer easily pass through the collapsed glycan network from the dermis to the epidermis. Skin healing slows and is eventually incomplete. Skin tone becomes blotchy and uneven. In tests, scientists at Ultra Aesthetics Labs, found that PP-4 stimulated collagen IV synthesis by 30 to 117% and Hyaluronic acid synthesis by 267%. Next they used image analysis to determine the affect PP-4 had on wrinkled skin after six months of daily application. The six-month results are listed below, though they noted that significant results were seen in two months.
Wrinkle depth improved: 17% Surface area containing deep wrinkles: 68% Surface area containing moderate wrinkles: 51% Density of wrinkled area improved: 47% Skin roughness: 16% Main wrinkle volume: 24% Matrixyl 3000 is an anti-aging skin treatment that promotes collagen production while stimulating fibroblast cells (the cells that in the skin that manufacture collagen), enabling them to significantly reduce the appearance of wrinkles. Matrixyl 3000 is a combination of two peptides, Palmitoyl Pentapeptide -4 (PP4) and Palmitoyl Tetrapeptide-7 (PT7). Matrixyl 3000® promotes collagen production while stimulating fibroblast cells in the skin, enabling them to significantly reduce the appearance of wrinkles.
In clinical trials the cream was applied daily for 56 days, containing a 3% concentration of Matrixyl 3000. The following was achieved:
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Glycation is the process by which glucose links with proteins and causes them to bind together, Glycation affects the skin's support system-collagen, elastin and other proteins-and leads to wrinkles, sagging, loss of youthful contours and uneven skin tone. PT-7 works by suppressing the production of interleukins in the skin which are a precursor to the process of glycation. Directions: Apply a small amount to the fingers and apply to face massaging gently into the skin. Use daily. The Day cream absorbs quickly allowing you to apply make-up if you wish. Day-Derm Ingredients: Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Hyaluronic Acid, Niacinamide, Water, Glycerine, Cherry Kernel Oil Glyceryl Stearate, Cetyl Alcohol, Sucrose Stearate, Sucrose Tristearate Jojoba Seed OIl, Hydrolised Jojoba Esters, Borage Seed Oil, Isoamyl Laurate, Isoamyl Cocoate, Tridecyl Stearate, Neopentyl Glycol Dicaprylate/Dicaprate, Tridecyl Trimellitate, Cetyl Esters, Sorbitan Oleate, Lysolecithin & Sclerotium Gum, Xanthan Gum, Pullulan, Benzyl Alcohol, Dehydoacetic Acid, Benzoic Acid, Sorbic Acid, Tocopherol, Citric Acid Rose Essential Oil, (Citral Eugenol Geranoil Citronellol Farnesol Linalool)
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